Ajax Harwood Clinic

Pregnenolone

This test doesn't have a proven medical use for the reasons people usually ask about it.

What this test is

Pregnenolone is a hormone your body makes first, and it is used to build cortisol and other hormones. Some clinics measure it to check whether your adrenal glands are keeping up with stress. No medical guideline we found supports this test for tiredness, memory or hormone balance. There is also no normal range linked to a recognized illness, so an unusual result is hard to explain or act on. Your symptoms are still worth looking into. Your doctor can check for known causes like poor sleep, low iron, thyroid problems, low B12 or low mood.

Want to see the full clinical reasoning? The reference we use for this test is open to anyone — it is detailed and written for clinicians, and you are welcome to read it.

Open the clinician reference →

Looking for other tests, or more on a condition an ND raised? Explore ask.ajaxharwoodclinic.com →

General health information for Ajax Harwood Clinic patients and the public — not medical advice, and not a substitute for seeing your own doctor. Last reviewed 2026-09-23.