Ajax Harwood Clinic
DHEA-S (adrenal hormone) test
Full name: DHEA-S (dehydroepiandrosterone sulfate)
This test is useful only in specific situations — it's not right for everyone who asks about it.
What this test is
DHEA-S is a hormone made mostly by your adrenal glands. This blood test is truly useful in some cases. For example, it helps when a woman has new facial or body hair, acne, or irregular periods. These can point to high male-type hormones. Or a doctor is checking for a rare adrenal growth. In these cases, DHEA-S helps find the cause. It is less useful as a plain check for low energy. Levels vary a lot between healthy people. A low number does not reliably explain tiredness. It also does not mean you need DHEA pills. Saliva and urine versions exist but are less standard.
Want to see the full clinical reasoning? The reference we use for this test is open to anyone — it is detailed and written for clinicians, and you are welcome to read it.
Open the clinician reference →Looking for other tests, or more on a condition an ND raised? Explore ask.ajaxharwoodclinic.com →
General health information for Ajax Harwood Clinic patients and the public — not medical advice, and not a substitute for seeing your own doctor. Last reviewed 2026-09-23.