Ajax Harwood Clinic
CA-125 (Cancer Antigen 125)
This test is useful only in specific situations — it's not right for everyone who asks about it.
What this test is
CA-125 is a blood test. Some people call it the ovarian cancer marker. It works best when you already have a lump near your ovaries. Doctors check it along with an ultrasound. This helps decide if you need to see a specialist. It is not a good test for healthy women with no symptoms. Many things besides cancer can raise CA-125. These include endometriosis, fibroids, or even a normal period. In early ovarian cancer, the level is often normal too. Big studies show that screening healthy women does not save lives. It can lead to surgery after a false alarm. If ovarian cancer runs in your family, ask about genetic testing instead.
Want to see the full clinical reasoning? The reference we use for this test is open to anyone — it is detailed and written for clinicians, and you are welcome to read it.
Open the clinician reference →Looking for other tests, or more on a condition an ND raised? Explore ask.ajaxharwoodclinic.com →
General health information for Ajax Harwood Clinic patients and the public — not medical advice, and not a substitute for seeing your own doctor. Last reviewed 2026-09-23.