Ajax Harwood Clinic
Antinuclear antibody (ANA)
This test is useful only in specific situations — it's not right for everyone who asks about it.
What this test is
ANA stands for antinuclear antibody. It is a blood test for lupus. Lupus is a disease where the immune system attacks your own body. This test works best when you have clear signs. These include certain joint pain, a sun-triggered rash, or unexplained problems with blood counts or kidneys. Here is something important. About one in seven healthy people test positive for ANA. They have no disease at all. So a positive test without a clear reason is often a false alarm, not real lupus. If you do have signs of lupus, this is the right first test. A positive result is then worth following up.
Want to see the full clinical reasoning? The reference we use for this test is open to anyone — it is detailed and written for clinicians, and you are welcome to read it.
Open the clinician reference →Looking for other tests, or more on a condition an ND raised? Explore ask.ajaxharwoodclinic.com →
General health information for Ajax Harwood Clinic patients and the public — not medical advice, and not a substitute for seeing your own doctor. Last reviewed 2026-09-23.